I've installed .100 just a few hours ago and from inital testing:

Applications that doesn't work:
Facebook 1.6
BBWeather
Viigo for Blackberry 3.1.330.0 - Uncaught exception: java.lang.NullPointerException

Applications that does work:
Google Map 3.0.2
Slacker Radio 2.0.2
iheartradio 1.0
Pageonce Assistant 2.1.0
ScoreMobile for Blackberry 1.0
Opera Mini 4.2
Bolt 1.04
Blackberry App World 1.0.0.28
Crackberry App Store 1.04.165

I install this OS hoping for the new BB Messenger that allows avatar and proximity sensing but instead I got BB Messenger 4.7. Did this happen to anyone else?