See EDIT below first
Dave, welome to the group.
First, is there a reason you are using an old version of desktop manager? If you are using an old version of Microsoft Outlook, that would be a good reason. But make sure you use the SP2 or SP3 version of 4.2.
Second, I think (not sure) desktop manager 4.X versions show disabled when the blackberry is not connected, and then switch from disabled to connected when the blackberry connects.
When you installed desktop manger, did you select the personal (BIS) option? You did not select the BES or the redirector option, correct?
Did the installation go ok? Does desktop manager lauch and run satisfactorily otherwise, with no error messages? If so, try different USB ports on the computer. Don't use a hub, do use a USB connection on the keyboard. It is advised to use a USB on the back of the box if you are using a desktop, if you are having trouble. If you are using a laptop, you might want to try using a desktop if you have one available.
EDIT: Is it actually a notification window you are seeing with, Disabled - BlackBerry Desktop Manager ? If so, how about the following: Clock ok. Click Connection Settings. Select USB in the drop down menu. Then connect the blackberry. (If you have a password on the blackbery, you will have to enter it in both desktop manager and the blackberry when prompted.) You may have to select "dectect" on the computer.
You should consider using the latest desktop manager if there is no reason for you to stick with the old version.
Last edited by aiharkness : 01-03-2010 at 07:58 AM.