I came from the Palm side of the house. Waited until August to buy the Pre from Sprint. Had it lock up on me a few times, and once with a critical patient. Only way out of it was to do a battery pull. Luckily I had one of the company Nextels, and I was able to reconnect to the Doc at the receiving hospital and continue care. I also noticed that the Pre would become unbearably warm during use.
Maybe I just had a dud, but my wife's Pre was experiencing the same problems.
Ultimately I switched to a Tour, and she switched to an LG Lotus. Both of us are tickled pink with our choices. With me being a bit of a g33k, I like being able to upgrade OS's, etc. Granted I felt that the Tour's factory OS was not what it should be, especially in light of the upgrades(.230 was nice, .419 is even better). But I am overall satisfied with my phone. In fact, I have even managed to switch some of my long standing IPhone fanboy friends over to various BB platforms.