It depends ... are you using Exchange? Perhaps Domino? Maybe you're even using GroupWise. Perhaps you're running in a virtual environment, maybe you've got a local MSDE installation ... who knows, maybe SQL 2005 locally on the BES.
Unfortunately you haven't provided any of this information, or really any information about your configuration except for the fact that you're running "the latest BES". I doubt you're running the latest BES; perhaps the latest GA version.
Provide some details if you want assistance.
Database Server Platform
Database Server locally / remote
Searching the links in my signature might help you too; ya know, in case you didn't want to provide any more info.