Is there any software that allows me to sync with my home and office Outlook (email, notes, tasks, calendar) and keep the two separate? I'd like to be able to toggle between the two without intermingling or overwriting email, tasks, etc.

One thread per topic.
Not three.

Thank you.

Apparently OP thinks this is a different question. So I've re-opened it.

Good luck.

If you are looking to do it via cable, you can use the desktop manager that came with your BB. If I understand your question this should not be very hard. Whichever computer you want to keep updated set the sync to two way. For the computer that you want to not change the information, set the sync to one way only, BB to computer.

However, you can NOT keep the data separate. There is one address book. One calendar.

Correct