I have run into a couple cases where, after the DM finishes syncronizing the handheld, an error pops up saying something like "Unable to complete request". When you go to look at the log file, one does not exist and the path to the location of the file is truncated (c:\docume~1\user\applic~1\resear~1\blackbe~1\ and so on).

Is there a place where you can change the path to the log? I'm just guessing that this may be the problem so if you have any other ideas, I'm open.

I would FULLY delete and re-install desktop manager. I've found that Desktop Manager does not fully remove itself all the time when you un-install.

Make sure that after you run the un-install that you delete:
c:\program files\research in motion

Also, delete any registry entries as follows:
HKEY_LOCAL_MACHINE\SOFTWARE\Research in Motion
HEY_CURENT_USER\SOFTWARE\Research in Motion

Re-install and see if that fixes the issue

Ok. Finally got arouind to trying this. Deleted the app. Removed the registry keys, even ran regclean to clean out the registry. Reinstalled the application and the same error happened. I was able to isolate the fact that it has to do with the creation of the log file.... but that's about it.