I tried the DM version 4.3 and it solved the problem,
Ever since I got my curve ( about 2 weeks), I have not been able to use my Desktop Manager's Application Loader (aka Application Removal).
I tried everything that this forum suggested, but still no result, I have to use OTA for all my apps .
Finally when I decided to try the version 4.3, I was finally able to "upload" the application to my phone.
so try it, it may work for you