Found this on RIM Knowledgebase.
Summary
This article applies to the following:
BlackBerry Enterprise Server™ version 4.0 Service Pack 1 and Service Pack 2
Integration with Microsoft® Exchange
Microsoft Windows® 2003 Service Pack 1
SDR55259
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Problem
When you upgrade the BlackBerry Enterprise Server version 4.0 Service Pack 1 to version 4.0 Service Pack 2 on a computer running Windows 2003 Service Pack 1, the upgrade fails and you receive the following message:
Some files that need to be updated are currently in use.
The file listed in use is BlackBerry Enterprise Server Installation.
The BlackBerry Manager log displays the following:
TServerManagerImpExch::OpenServiceInterface - OpenService failed, The specified service does not exist as an installed service. 0x424, ServiceName='BBUserAdminService'
Workaround
Click Ignore to continue the upgrade.
This is a previously reported issue that has been escalated internally to our development team. No resolution time frame is currently available.
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