I had the same issue on launch day guys... wouldn't run on my PC... but, loaded just fine or my Mac...
2 fixes...
1- I loaded it on my Mac and dloaded the pdf file (8300 User's Guide) and emailed it to myself on my PC.
2- just dload the Desktop Mgr software from Blackberry.com for the Curve... it will be the newest version anyway!!!
Everything has been working just fine for me since... Best!