Since the BlackBerry works in other computers then it can't be the device, it sounds like something local.
Have you tried, different USB cables/Ports.
Also might want to check what other applications are running on the computer maybe something is interfering.
Also might want to include some more information, such what version of the BlackBerry Desktop Manager you are using, what os is running on the computer in question.
Posted via BlackBerryForums.com Mobile
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