If you are using the same database and service account, there will be no reason to do anything after the installation - however, that method should be considered only an application reinstallation and not a system/environment reinstallation.
If you are going to remove the BES software, start over with a new service account and database, then you'll need to do a security wipe on all of the handhelds and then readd those users and reactivate them.
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