Depends a bunch on how often you use wi-fi, and how hard you are on your battery. If you have wi-fi and BT on all the time, it will make a noticeable difference vs. having them both off all the time.
There are aftermarket apps that will turn each on or off for you based on your GPS location, so when you arrive home, wifi is turned on, and when you leave, it's turned off. But if battery life isn't a problem, I'd smile and leave it all alone.